L. A. Abriata

MolecularWebXR: Multiuser discussions about chemistry and biology in immersive and inclusive VR

MolecularWebXR enables multiuser VR/AR discussions about chemistry and biology in immersive environments accessible via web browsers and consumer devices.

A humoral stress response protects Drosophila tissues from antimicrobial peptides

This study identifies Turandot stress proteins that protect Drosophila tissues from antimicrobial peptide-induced damage by binding phosphatidylserine and inhibiting AMP pore formation.

Structure and functionality of a multimeric human COQ7:COQ9 complex

The paper presents the structure and functional analysis of a multimeric COQ7:COQ9 complex involved in CoQ biosynthesis, revealing its mechanism for accessing hydrophobic precursors and coordinating CoQ synthesis.

Three-dimensional structure of the single domain cupredoxin AcoP

This paper determines the 3D structure of AcoP, a cupredoxin from Acidithiobacillus ferrooxidans, revealing unique structural features and copper coordination that explain its redox properties and function.

3D architecture and structural flexibility revealed in the subfamily of large glutamate dehydrogenases by a mycobacterial enzyme

The paper reveals the 3D architecture and structural flexibility of a mycobacterial large glutamate dehydrogenase, identifying novel structural features and potential regulatory domains.

Investigating crosstalk among PTMs provides novel insight into the structural basis underlying the differential effects of Nt17 PTMs on mutant Httex1 aggregation

This study investigates how PTMs in Nt17 of mutant Httex1 affect aggregation, showing that oxM8 delays aggregation and that combinations with AcK6 inhibit fibrillization, with structural insights from spectroscopy and simulations.

Site-specific phosphorylation of Huntingtin exon 1 recombinant proteins enabled by the discovery of novel kinases

This paper introduces a method to produce site-specifically phosphorylated Httex1 proteins using novel kinases and SUMO-fusion purification, enabling further study of phosphorylation's role in Httex1 function.