Author

E. M. Lisabeth

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:proteomics· 1

Frequent Co-Authors

R. R. Neubig· 2 shared S. A. Misek· 2 shared S. D. Larsen· 2 shared T. S. Dexheimer· 2 shared B. R. Martin· 1 shared D. A. Fox· 1 shared D. Kahl· 1 shared D. Khanna· 1 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersCancer Biology

R. R. Neubig

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2 papers

Recent·Most cited

Rho-mediated gene transcription promotes BRAF inhibitor resistance in de-differentiated melanoma cells

S. A. Misek, K. M. Appleton, T. S. Dexheimer, E. M. Lisabeth, R. Lo, S. D. Larsen, K. Gallo, R. R. Neubig

This study identifies RhoA-mediated gene transcription as a mechanism of BRAF inhibitor resistance in melanoma, showing that targeting this pathway can re-sensitize resistant cells to vemurafenib.

bioRxiv · Mar 31, 2019 · PreprintCancer Biology

Identification of Pirin as a Molecular Target of the CCG-1423/CCG-203971 Series of Anti-Fibrotic and Anti-Metastatic Compounds

E. M. Lisabeth, D. Kahl, I. Gopallawa, S. E. Haynes, S. A. Misek, P. L. Campbell, T. S. Dexheimer, D. Khanna, D. A. Fox, X. Jin, B. R. Martin, S. D. Larsen, R. R. Neubig

This study identifies pirin as the molecular target of the CCG-1423/CCG-203971 compounds, showing its role in modulating MRTF-dependent gene expression and fibrosis.

bioRxiv · Oct 31, 2018Pharmacology & Toxicology