Substrate-interacting pore loops of two ATPase subunits determine the degradation efficiency of the 26S proteasome
A. Martin, E. M. Lopez-Alfonzo, A. Saurabh, S. Zarafshan, S. Presse
This study investigates how pore-1 loops of ATPase subunits in the 26S proteasome affect substrate degradation efficiency using biochemical and single-molecule assays with yeast proteasomes.
bioRxiv · Dec 14, 2023Biochemistry