Author

A. Saurabh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 4 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:Bayesian inference· 4 Assay:fluorescence / live-cell microscopy· 3 Research Focus:cell type annotation· 2 Research Focus:benchmarking· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:imputation· 1

Frequent Co-Authors

S. Presse· 4 shared I. Sgouralis· 3 shared M. Fazel· 3 shared M. Safar· 3 shared A. Martin· 1 shared B. Sarkar· 1 shared C. Kural· 1 shared C. Thompson· 1 shared

Activity by Year

2022-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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4 shared papersBiophysics

S. Presse

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Approaching Maximum Resolution in Structured Illumination Microscopy via Accurate Noise Modeling

A. Saurabh, P. T. Brown, J. S. Bryan, Z. R. Fox, R. Kruithoff, C. Thompson, C. Kural, D. P. Shepherd, S. P. Presse

This paper introduces B-SIM, an unsupervised Bayesian framework for structured illumination microscopy that improves resolution and contrast by accurately modeling noise, outperforming existing methods in both simulated and experimental data.

npj Imaging · Jan 31, 2025Peer-reviewedBiophysics

Substrate-interacting pore loops of two ATPase subunits determine the degradation efficiency of the 26S proteasome

A. Martin, E. M. Lopez-Alfonzo, A. Saurabh, S. Zarafshan, S. Presse

This study investigates how pore-1 loops of ATPase subunits in the 26S proteasome affect substrate degradation efficiency using biochemical and single-molecule assays with yeast proteasomes.

bioRxiv · Dec 14, 2023Biochemistry

Single Photon smFRET. II. Application to Continuous Illumination

A. Saurabh, M. Safar, M. Fazel, I. Sgouralis, S. Presse

The paper applies a Bayesian nonparametric framework to analyze smFRET data under continuous illumination, learning system states and kinetics from synthetic and experimental datasets.

bioRxiv · Jul 20, 2022Biophysics

Single Photon smFRET. III. Application to Pulsed Illumination

M. Safar, A. Saurabh, B. Sarkar, M. Fazel, K. Ishii, T. Tahara, I. Sgouralis, S. Presse

This paper applies a Bayesian nonparametric framework to analyze single photon, single molecule FRET data under pulsed illumination, addressing uncertainties and noise sources in Holliday junction experiments.

bioRxiv · Jul 20, 2022Biophysics

Single Photon smFRET. I. Theory and Conceptual Basis

A. Saurabh, M. Fazel, M. Safar, I. Sgouralis, S. Presse

This paper introduces a Bayesian nonparametric framework and software for analyzing single photon smFRET data, addressing unknown system states and noise sources.

bioRxiv · Jul 20, 2022Biophysics