An autoinhibitory clamp of actin assembly constrains and directs synaptic endocytosis
S. J. Del Signore, C. F. Kelley, E. M. Messelaar, T. Lemos, M. F. Marchan, B. Ermanoska, M. Mund, T. G. Fai, M. Kaksonen, A. A. Rodal
The paper identifies an autoinhibitory mechanism that limits actin assembly to specific synaptic endocytic events by regulating interactions between Nwk, Dap160, and WASp.
bioRxiv · Mar 6, 2020Cell Biology