M. Kaksonen

An evolutionary cell biology perspective into the diverging mechanisms of clathrin-mediated endocytosis in dikarya fungi

This study uses dikarya fungi to investigate evolutionary differences in clathrin-mediated endocytosis, revealing phenotypic variations and their implications for mechanistic understanding.

Bsp1, a fungal CPI motif protein, regulates actin filament capping in endocytosis and cytokinesis

This study identifies Bsp1, a fungal CPI motif protein, as a regulator of actin filament capping during endocytosis and cytokinesis in budding yeast.

Spatio-temporal regulation of endocytic protein assembly by SH3 domains in yeast

The paper investigates SH3 domain-mediated regulation of endocytic protein assembly in yeast using mutagenesis and live-cell imaging, revealing dynamic interactions and recruitment mechanisms.

Superresolution microscopy reveals partial preassembly and subsequent bending of the clathrin coat during endocytosis

The paper uses superresolution microscopy to show clathrin coats partially assemble on flat membranes before bending, and introduces a model to explain this process.

Regulation of membrane scission in yeast endocytosis

This study investigates the role of Rvs BAR and SH3 domains in yeast endocytic scission, showing their importance in membrane invagination and vesicle formation.

An autoinhibitory clamp of actin assembly constrains and directs synaptic endocytosis

The paper identifies an autoinhibitory mechanism that limits actin assembly to specific synaptic endocytic events by regulating interactions between Nwk, Dap160, and WASp.

Phase separation of Ede1 promotes the initiation of endocytic events

The paper shows that Ede1 phase separation forms condensates that recruit endocytic proteins and initiate endocytic events.

Type-I myosins promote actin polymerization to drive membrane bending in endocytosis

This study shows type-I myosins promote actin polymerization to drive membrane bending during endocytosis in budding yeast.

The contributions of the actin machinery to endocytic membrane bending and vesicle formation

This study investigates how actin network components contribute to endocytic membrane bending and vesicle formation in yeast using genetic mutants and hybrid imaging.

Systematic analysis of the molecular architecture of endocytosis reveals a nanoscale actin nucleation template that drives efficient vesicle formation

The paper uses high-throughput superresolution microscopy to analyze endocytic protein organization in yeast, revealing a WASP nano-template that enhances actin nucleation efficiency during vesicle formation.