Iron-loaded deferiprone can support full hemoglobinization of cultured red blood cells in the absence of transferrin
J. S. Gallego-Murillo, N. Yagcı, E. M. Pinho, A. Abeijon-Valle, A. Wahl, E. van den Akker, M. von Lindern
This study shows that iron-loaded deferiprone can replace holotransferrin in erythroid cultures, supporting reticulocyte differentiation and erythroblast expansion.
bioRxiv · Aug 2, 2021 · PreprintCell Biology