An optogenetic method for interrogating YAP1 and TAZ nuclear-cytoplasmic shuttling
A. M. Dowbaj, R. P. Jenkins, J. M. Heddleston, A. Ciccarelli, T. Fallesen, K. Hahn, M. Montagner, E. M. Sahai
This paper introduces an optogenetic method to measure nuclear-cytoplasmic shuttling rates of YAP1 and TAZ, showing phosphorylation enhances nuclear export and that import/export rates are correlated within cells.
bioRxiv · Jun 8, 2020Cell Biology