Multi-site assessment of reproducibility in high-content live cell imaging data
J. Hu, X. Serra-Picamal, G.-J. Bakker, M. V. Troys, S. Winograd-katz, N. Ege, X. Gong, Y. Didan, I. Grosheva, O. Polansky, K. Bakkali, E. V. Hamme, M. v. Erp, M. Vullings, F. Weiss, , S. Stromblad
This study assesses reproducibility in high-content live cell imaging data across multiple sites and identifies sources of variability, showing that batch correction improves meta-analysis of perturbation experiments.
bioRxiv · Nov 18, 2022 · PreprintCell Biology