Author

E. Malinen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell type annotation· 2 Assay:imaging· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

N. F. J. Edin· 4 shared T. M. Soland· 4 shared I. S. Juvkam· 3 shared O. Zlygosteva· 3 shared H. K. Galtung· 2 shared A. Eek Mariampillai· 1 shared A. Gilbert· 1 shared A. M. Rykkelid· 1 shared

Activity by Year

2022-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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4 shared papersCancer Biology

N. F. J. Edin

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Interferon signaling is enhanced by ATR inhibition in glioblastoma cells irradiated with X-rays, protons or carbon ions

G. E. Rodland, M. Temelie, A.-M. Serban, A. Eek Mariampillai, N. F. J. Edin, E. Malinen, A. Gilbert, F. Chevalier, D. I. Savu, R. G. Syljuasen

This study shows ATR inhibition enhances IFN signaling in glioblastoma cells after X-ray, proton, and carbon-ion irradiation, with stronger effects at higher LET.

bioRxiv · Jun 12, 2024Cancer Biology

Synergistic effects of combing proton- or X-irradiation with anti-PDL1 immunotherapy in two murine oral cancers

A. M. Rykkelid, P. M. Sinha, C. A. Folefac, M. R. Horsman, B. S. Sorensen, T. M. Soland, O. J. F. Schreurs, E. Malinen, N. F. J. Edin

This study compares the effectiveness of X-ray and proton irradiation combined with anti-PDL1 immunotherapy in two murine oral cancer models, finding greater synergy with protons.

bioRxiv · Sep 13, 2023 · PreprintCancer Biology

TGF-β3 increases the severity of radiation-induced oral mucositis and salivary gland fibrosis in a mouse model

I. Hanson, I. S. Juvkam, O. Zlygosteva, T. M. Soland, H. Galtung, E. Malinen, N. F. J. Edin

This study shows that TGF-β3 treatment during radiation therapy in mice worsens oral mucositis, weight loss, and salivary gland fibrosis.

bioRxiv · Sep 12, 2023Biophysics

Fractionated irradiation of murine salivary glands resulted in focal acinar cell atrophy, immune cell infiltration, fibrosis, and hyposalivation

I. S. Juvkam, O. Zlygosteva, E. Malinen, N. F. J. Edin, H. K. Galtung, T. M. Soland

This study examines radiation-induced changes in murine salivary glands, finding reduced saliva production, fibrosis, acinar cell atrophy, and immune cell infiltration after fractionated irradiation.

bioRxiv · Sep 5, 2023 · PreprintCell Biology

A Preclinical Model to Investigate Normal Tissue Damage Following Fractionated Radiotherapy to the Head and Neck

I. S. Juvkam, O. Zlygosteva, D. Arous, H. K. Galtung, E. Malinen, T. M. Soland, N. J. Edin

This study establishes a preclinical model to assess normal tissue damage from head and neck radiotherapy, finding that 75 Gy induces acute effects similar to human patients.

bioRxiv · May 19, 2022Cancer Biology