A Primase-Induced Conformational Switch Controls the Stability of the Bacterial Replisome
E. Monachino, S. Jergic, J. S. Lewis, Z.-Q. Xu, A. T. Y. Lo, V. L. O Shea, J. M. Berger, N. E. Dixon, A. M. van Oijen
This study identifies a primase-induced conformational switch that enhances the stability of the bacterial replisome by strengthening the interaction between the polymerase holoenzyme and the replicative helicase.
bioRxiv · Nov 13, 2018Biochemistry