Endoplasmic reticulum-targeting but not translation is required for mRNA balancing in trypanosomes
E. O. Aroko, M. B. Soale, C. Batram, N. G. Jones, M. Engstler
This study shows that ER targeting, not translation, regulates VSG mRNA levels in trypanosomes, suggesting ER feedback controls mRNA amounts to prevent secretory pathway overload.
bioRxiv · May 5, 2021 · PreprintMicrobiology