Author

E. O. Karakaslar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

A. M. Otte· 1 shared C. J. Halkes· 1 shared E. B. van den Akker· 1 shared E. Sanchez-Lopez· 1 shared H. Veelken· 1 shared J. F. Severens· 1 shared J. J. van Dongen· 1 shared M. Griffioen· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A. M. Otte

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1 paper

Recent·Most cited

Single cell guided deconvolution of bulk transcriptomics recapitulates differentiation stages of acute myeloid leukemia and predicts drug response

E. O. Karakaslar, J. F. Severens, E. Sanchez-Lopez, P. A. van Veelen, M. Zlei, J. J. van Dongen, A. M. Otte, C. J. Halkes, P. van Balen, H. Veelken, M. J. Reinders, M. Griffioen, E. B. van den Akker

This study uses single-cell data to deconvolute bulk RNA-seq samples of AML, showing that differentiation stages can be reconstructed and used to predict drug responses like Venetoclax resistance.

bioRxiv · Dec 9, 2022 · PreprintCancer Biology