Author

E. P. Kadar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 1 Organism:virus· 1

Frequent Co-Authors

R. S. Obach· 2 shared A. D. Mesecar· 1 shared A. K. Chatterjee· 1 shared A. S. Anderson· 1 shared B. Boras· 1 shared B. J. Anson· 1 shared B. T. George· 1 shared C. Allerton· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersPharmacology & Toxicology

R. S. Obach

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Author profile →

2 papers

Recent·Most cited

A Novel Milli-fluidic Liver Tissue Chip with continuous Recirculation for Predictive pharmacokinetics Applications

S. A. P. Rajan, J. Sherfey, S. Ohri, L. Nichols, J. T. Smith, P. Parekh, E. P. Kadar, F. Clark, B. T. George, L. Gregory, D. Tess, J. R. Gosset, J. Liras, E. Geishecker, R. S. Obach, M. Cirit

This paper develops a milli-fluidic liver tissue chip with continuous recirculation to improve predictive pharmacokinetics by enhancing physiological relevance and long-term culture stability.

bioRxiv · Jul 24, 2023 · PreprintPharmacology & Toxicology

Discovery of a Novel Inhibitor of Coronavirus 3CL Protease as a Clinical Candidate for the Potential Treatment of COVID-19

B. Boras, R. M. Jones, B. J. Anson, D. Arenson, L. Aschenbrenner, M. A. Bakowski, N. Beutler, J. Binder, E. Chen, H. Eng, J. Hammond, R. Hoffman, E. P. Kadar, R. Kania, E. Kimoto, , M. E. McGrath

This study identifies PF-00835321 as a potent inhibitor of SARS-CoV-2 3CL protease with in vitro antiviral activity and clinical evaluation potential.

bioRxiv · Sep 12, 2020 · PreprintPharmacology & Toxicology