Author

R. M. Jones

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Immunology· 1 Pathology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

C. R. Naudin· 2 shared A. D. Mesecar· 1 shared A. F. Coskun· 1 shared A. K. Chatterjee· 1 shared A. R. Reedy· 1 shared A. R. VanderArk· 1 shared A. S. Anderson· 1 shared A. Toma· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersPathology

C. R. Naudin

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Author profile →

5 papers

Recent·Most cited

Microbial Changes occurring during oronasal fistula wound healing

S. L. Goudy, H. L. Bradley, C. A. Gacasan, A. Toma, C. R. Naudin, W. M. Wuest, M. L. Tomov, V. Serpooshan, A. F. Coskun, R. M. Jones

This study shows that an oro-nasal fistula in mice causes microbiome dysbiosis, which hinders healing, but delivering Lactococcus lactis subsp. cremoris promotes healing and restores microbial balance.

Microorganisms · Feb 2, 2025Peer-reviewedPathology

The histone lysine demethylase KDM5C fine-tunes gene expression to regulate dendritic cell heterogeneity and function

H. Guak, M. J. Weiland, A. R. VanderArk, L. Zhai, K. Lau, B. Mabvakure, M. Corrado, P. Davidson, S. Compton, L. DeCamp, C. Scullion, R. M. Jones, S. Nowinski, C. M. Krawczyk

This study shows KDM5C regulates dendritic cell (DC) heterogeneity and function by modulating epigenetic programming and subset balance, affecting immune responses to infection.

bioRxiv · May 28, 2023 · PreprintImmunology

Lactococcus lactis sb. cremoris orchestrates signal events in the gut epithelium via TLR2 to promote tissue restitution

C. R. Naudin, J. A. Owens, L. C. Askew, R. N. Khan, C. D. Scharer, J. D. Matthews, L. Luo, J. Kim, A. R. Reedy, M. E. Barbian, R. M. Jones

This study shows that Lactococcus lactis subsp. cremoris promotes gut tissue repair via TLR2 signaling, enhancing epithelial migration and cytoprotection.

bioRxiv · Dec 2, 2021 · PreprintMicrobiology

Discovery of a Novel Inhibitor of Coronavirus 3CL Protease as a Clinical Candidate for the Potential Treatment of COVID-19

B. Boras, R. M. Jones, B. J. Anson, D. Arenson, L. Aschenbrenner, M. A. Bakowski, N. Beutler, J. Binder, E. Chen, H. Eng, J. Hammond, R. Hoffman, E. P. Kadar, R. Kania, E. Kimoto, , M. E. McGrath

This study identifies PF-00835321 as a potent inhibitor of SARS-CoV-2 3CL protease with in vitro antiviral activity and clinical evaluation potential.

bioRxiv · Sep 12, 2020 · PreprintPharmacology & Toxicology

Impacts of Deep-Sea Mining on Microbial Ecosystem Services

B. N. Orcutt, J. Bradley, W. J. Brazelton, E. J. Estes, J. M. Goordial, J. A. Huber, R. M. Jones, N. Mahmoudi, J. J. Marlow, S. Murdock, M. Pachiadaki

This paper evaluates the potential impacts of deep-sea mining on microbial ecosystem services, highlighting varying levels of impact and recommending baseline assessments and protected areas.

bioRxiv · Nov 6, 2018Microbiology