Ultra-deep sequencing differentiates patterns of skin clonal mutations associated with sun-exposure status and skin cancer burden
L. Wei, S. Christensen, M. Fitzgerald, J. Graham, N. Hutson, C. Zhang, Z. Huang, Q. Hu, F. Zhan, J. Xie, J. Zhang, S. Liu, E. Remenyik, E. Gellen, O. R. Colegio, , G. Paragh
This study uses ultra-deep sequencing to analyze clonal mutations in sun-exposed and non-sun-exposed skin, finding higher UV-signature mutations and mutation burden in sun-exposed samples.
bioRxiv · Jan 10, 2020 · PreprintCancer Biology