J. Graham

Sympathetic innervation of interscapular brown adipose tissue is not a predominant mediator of oxytocin-elicited reductions of body weight and adiposity in male diet-induced obese mice

This study shows that sympathetic innervation of interscapular brown adipose tissue is not required for oxytocin-induced weight loss and thermogenesis in diet-induced obese mice.

Silencing of a raspberry homologue of VRN1 is associated with disruption of dormancy induction and misregulation of subsets of dormancy-associated genes.

This study identifies a VRN1 homologue in raspberry that, when silenced by upstream insertions in Glen Dee, causes dormancy misregulation and altered gene expression.

Raspberry plant stress detection using hyperspectral imaging

This study uses hyperspectral imaging to detect below ground stress in raspberry plants by analyzing spectral reflectance differences across genotypes and stress treatments.

Identification of genetic loci in lettuce mediating quantitative resistance to fungal pathogens

The paper identifies genetic loci in lettuce conferring quantitative resistance to fungal pathogens and predicts molecular mechanisms through transcriptome profiling.

A Longitudinal Study of Dominant E. coli Lineages and Antimicrobial Resistance in the Gut of Children Living in an Upper Middle-income Country

This study tracks E. coli lineages and antimicrobial resistance in children's gut over a year, finding dominant strains are transient and resistance patterns vary without clear selective pressure.

Genomic epidemiology of Mycobacterium bovis infection in sympatric badger and cattle populations in Northern Ireland.

This study sequenced M. bovis isolates from badgers and cattle in Northern Ireland to analyze genomic epidemiology, finding an endemic lineage with low diversity and evidence of interspecies transmission.

Analytical validation and performance characteristics of a 48-gene next-generation sequencing panel for detecting potentially actionable genomic alterations in myeloid neoplasms

The paper validates a 48-gene NGS panel for detecting actionable genomic mutations in myeloid neoplasms, showing high sensitivity and specificity.

A longitudinal study of E. coli lineages and antimicrobial resistance in Ecuadorian children

This study tracks E. coli lineages and antimicrobial resistance in Ecuadorian children over a year, finding that most lineages are transient but some resistant strains persist for months.

Baseline T cell immune phenotypes predict virologic and disease control upon SARS-CoV infection

The paper shows that baseline T cell immune signatures in mice predict virologic and disease outcomes upon SARS-CoV infection.

Ultra-deep sequencing differentiates patterns of skin clonal mutations associated with sun-exposure status and skin cancer burden

This study uses ultra-deep sequencing to analyze clonal mutations in sun-exposed and non-sun-exposed skin, finding higher UV-signature mutations and mutation burden in sun-exposed samples.

Insights from Comparison of the Renal and Skin Single Cell Transcriptomes in Lupus Nephritis

This study uses scRNA-seq to analyze renal and skin biopsies from lupus nephritis patients, identifying IFN signatures and fibrotic pathways associated with disease heterogeneity and non-response.

Co-reviewing and ghostwriting by early career researchers in the peer review of manuscripts

This study examines co-reviewing and ghostwriting by early career researchers in peer review, finding common practices and ethical concerns.

Diverse commensal E. coli clones and plasmids disseminate antimicrobial resistance genes in domestic animals and children in a semi-rural community in Ecuador

This study identifies diverse plasmids and nonclonal dissemination of antimicrobial resistance genes among E. coli isolates from humans and domestic animals in a semi-rural Ecuadorian community.