Pancreatic tumor organoids for modeling in vivo drug response and discovering clinically-actionable biomarkers
l. huang, B. Bockorny, I. Paul, D. Akshinthala, O. Gandarilla, A. Bose, V. Sanchez-Gonzalez, E. Rouse, S. Lehoux, N. Pandell, J. Clohessy, J. Grossman, R. Gonzalez, S. Perea del Pino, G. Daaboul, , S. Muthuswamy
This paper demonstrates that pancreatic tumor organoids (PDOs) recapitulate PDX models' features and can identify clinically-actionable biomarkers in blood.
bioRxiv · Jan 28, 2019 · PreprintCancer Biology