Cabozantinib unlocks efficient in vivo targeted delivery of neutrophil-loaded nanoparticles into murine prostate tumors
K. Chaudagar, N. Landon-Brace, A. Solanki, H. M. Hieromnimon, E. Hegermiller, W. Li, Y. Shao, D. Wilkins, K. Bynoe, X.-L. Li, J. Clohessy, S. Ullas, J. Karp, A. Patnaik
This study shows cabozantinib enhances neutrophil-mediated delivery of nanoparticles to prostate tumors in mice, leading to higher NP accumulation in the tumor microenvironment.
bioRxiv · Apr 13, 2020Cancer Biology