Distant lymph nodes compensate for resected tumor-draining lymph nodes during cancer immunotherapy
L. Menzel, H. Zhou, J. W. Baish, M. J. O'Melia, L. B. Darragh, E. Specht, D. N. Effiom, J. Czapla, P.-j. Lei, J. J. Rajotte, L. Liu, M. R. Nikmaneshi, M. S. Razavi, M. G. Vander Heiden, J. M. Ubellacker, , T. P. Padera
The paper shows that removing tumor-draining lymph nodes does not impair immune checkpoint blockade response, as distant lymph nodes compensate for the loss.
bioRxiv · Sep 19, 2023Cancer Biology