Author

E. Vargas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

K. Prehoda· 2 shared A. Shaub-Maddox· 1 shared D. Cortes· 1 shared F. McNally· 1 shared K. McNally· 1 shared M. Panzica· 1 shared R. R. Penkert· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 11 mutual co-author links

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2 shared papersCell Biology

K. Prehoda

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3 papers

Recent·Most cited

Negative cooperativity underlies dynamic assembly of the Par complex regulators Cdc42 and Par-3

E. Vargas, K. Prehoda

The paper identifies negative cooperativity between Par-3 and Cdc42 in the Par complex, showing how their interaction mediates the transition from Par-3 to Cdc42 for complex polarization.

bioRxiv · Aug 12, 2022Cell Biology

Energetic determinants of the Par-3 interaction with the Par complex

R. R. Penkert, E. Vargas, K. Prehoda

This study identifies the energetic contributions of Par-3's PDZ domains to its interaction with the Par complex, showing each Par-3 molecule can recruit two Par complexes during cell polarization.

bioRxiv · Dec 10, 2021 · PreprintCell Biology

Spherical Spindle Shape Promotes Perpendicular Cortical Orientation by Preventing Isometric Cortical Pulling on both Spindle Poles during C. elegans Female Meiosis

E. Vargas, K. McNally, D. Cortes, M. Panzica, A. Shaub-Maddox, F. McNally

This study shows that spherical spindle shape in C. elegans female meiosis promotes perpendicular cortical orientation by preventing isometric cortical pulling on both poles and stabilizing round poles through dynein interactions.

bioRxiv · Apr 2, 2019Cell Biology