Author

E. Vassella

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Perren· 2 shared J. Phour· 2 shared A. Di Domenico· 1 shared B. Sharf Den Abu Fakher· 1 shared C. Nydegger· 1 shared C. P. Pipinikas· 1 shared C. Simillion· 1 shared C. Thirlwell· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

A. Perren

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Author profile →

3 papers

Recent·Most cited

Methods in cancer research: Assessing therapy response of spheroid cultures by life cell imaging using a Cost-Effective Live-Dead Staining Protocol

J. Phour, E. Vassella

The paper develops a cost-effective live-dead staining protocol for monitoring therapy response in spheroid cultures over 10 days using calcein-AM and Helix NP Blue.

bioRxiv · Apr 17, 2024Cancer Biology

Unlocking the potential of miR-19b in the regulation of temozolomide response in glioblastoma patients via targeting PPP2R5E, a subunit of the protein phosphatase 2A complex

E. Kashani, K. Hlavackova, S. Haemmig, M. C. Sadowski, J. Phour, U. Baumgartner, N. Mueller-Wirth, C. Trefny, B. Sharf Den Abu Fakher, C. Nydegger, T. Maragkou, P. Schucht, A. Perren, P. Zinn, M. Luedi, , E. Vassella

This study identifies miR-19b's role in TMZ resistance in GBM by targeting PPP2R5E, showing that miR-19b attenuation enhances TMZ efficacy in cell lines and xenografts.

bioRxiv · Jan 16, 2023Cancer Biology

Epigenetic landscape of pancreatic neuroendocrine tumours reveals distinct cells of origin and means of tumour progression

A. Di Domenico, C. P. Pipinikas, R. S. Maire, K. Bräutigam, C. Simillion, M. S. Dettmer, E. Vassella, C. Thirlwell, A. Perren, I. Marinoni

The paper uses DNA methylation profiling to identify cell origins and progression mechanisms in PanNETs, finding distinct epigenetic clusters associated with different cell types and clinical outcomes.

bioRxiv · Apr 8, 2020Cancer Biology