Patient-derived organoids from malignant pleural effusion to explore for alternative therapies in thoracic tumors
Rocio Ferreiro-Miguens, Isabel Diez-Grandio, Roi Soto-Feijóo, Lucía Ferreiro, Jorge Garcia, María Otero-Alén, Ihab Abdulkader, Beatriz Bernárdez, Eduardo Dominguez, Miguel Abal, Luis León‐Mateos
This study generates patient-derived organoids from malignant pleural effusions to assess chemotherapy sensitivity in thoracic tumors, revealing significant inter-model variability in treatment response.
bioRxiv · Mar 6, 2026 · PreprintCancer Biology