Luis León‐Mateos

This study generates patient-derived organoids from malignant pleural effusions to assess chemotherapy sensitivity in thoracic tumors, revealing significant inter-model variability in treatment response.

This study shows that red blood cells from cancer patients enhance tumour cell invasiveness and metastatic potential through gene and protein changes, suggesting PAK4 as a therapeutic target.

This study identifies mutation patterns, TMB, HLA haplotypes, and LINE-1 activation as potential biomarkers for predicting ICI response in NSCLC and MIBC.