Norovirus-mediated modification of the translational landscape via virus and host-induced cleavage of translation initiation factors.
Edward Emmott, Frederic Sorgeloos, Sarah L. Caddy, Surender Vashist, Stanislav Sosnovtsev, Richard Lloyd, Kate Heesom, Ian Goodfellow
This study shows noroviruses suppress host ISG translation by altering eukaryotic initiation factor composition through viral protease and caspase activity.
Molecular & Cellular Proteomics · Apr 1, 2017Peer-reviewedMicrobiology