Using Functional Genomic Data in Monocytes/Macrophages and Genotyping to Nominate Disease-Driving Single Nucleotide Polymorphisms and Target Genes in Juvenile Idiopathic Arthritis
Emma K. Haley, Gilad Barshad, Adam Youlin He, Edward Rice, Marc Sudman, Susan D. Thompson, Elizabeth A. Crinzi, Kaiyu Jiang, Charles G. Danko, James N. Jarvis
The paper identifies disease-driving SNPs in JIA risk haplotypes using functional genomic data and genotyping, and links them to target genes through chromatin interactions.
bioRxiv · Aug 19, 2024 · PreprintGenetics