Author

Efi Tsouri

The Netherlands Cancer Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Artur M Burylo· 1 shared Caroline L. Van Heijningen· 1 shared Laura E. KuiliD· 1 shared Mark C. de GooijeriD· 1 shared Olaf van TellingeniD· 1 shared Sanne B. SchageniD· 1 shared Yoran M LeteriD· 1 shared Zoey J TolboomiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperPharmacology & Toxicology

Artur M Burylo

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1 paper

Recent·Most cited

CSF1R inhibitors pexidartinib and sotuletinib induce rapid glial ablation despite their limited brain penetrability

Olaf van Tellingen, Zoey J Tolboom, Yoran M Leter, Efi Tsouri, Artur M Burylo, Caroline L. Van Heijningen, Sanne B. Schagen, Mark C. de Gooijer, Laura E. Kuil

This study shows that high-dose CSF1R inhibitors pexidartinib and sotuletinib rapidly deplete microglia despite limited brain penetration, with significant off-target effects on other immune and tissue cells.

bioRxiv · Oct 11, 2025 · PreprintPharmacology & Toxicology