Multiple Unfolded Protein Response pathways cooperate to link cytosolic dsDNA release to Stimulator of Interferon Gene (STING) activation
Tiancheng Hu, Yiping Liu, Jeremy Fleck, Cason R. King, Elaine Schalk, Zhenyu Zhang, Andrew Mehle, Judith A. Smith
This study identifies multiple UPR pathways that cooperate to link cytosolic dsDNA release to STING activation and IFN-β induction in response to ER stress.
Frontiers in Immunology · Jul 19, 2024Peer-reviewedImmunology