Author

Zhenyu Zhang

University of Wisconsin–MadisonORCID 0000-0003-4974-1400Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Zhenyu Zhang6 papers · Shenzhen Bay Laboratory

Biology Disciplines

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Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Assay:proteomics· 3 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Organism:chicken / avian· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Andrew MehleiD· 3 shared Adrianus C. M. BooniD· 1 shared Anthony K. L. LeungiD· 1 shared Cason R. KingiD· 1 shared Che-Yuan Chang· 1 shared Elaine Schalk· 1 shared Elizabeth M Feltman· 1 shared Gloria P. LarsoniD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersMicrobiology

Andrew MehleORCID

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3 papers

Recent·Most cited

MicrobiologyNature CommunicationsPeer-reviewedDec 17, 2025

Global remodeling of ADP-ribosylation by PARP1 suppresses influenza A virus infection

Zhenyu Zhang, Isabel R. Uribe, Kaitlin A. Davis…·Andrew Mehle

The paper shows influenza A virus infection increases global ADP-ribosylation, which inhibits viral replication, and identifies PARP1 as the main enzyme involved, with NS1 counteracting this effect.

10 citationstop 2%

humanproteomics

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MicrobiologybioRxivPreprintSep 16, 2024

A single ancestral ANP32 locus in ticks creates multiple protein variants that all support the Thogoto virus polymerase

Zhenyu Zhang, Thomas Nipper, Ishmael D. Aziati…·Andrew Mehle

The paper identifies a single ANP32 locus in ticks that generates multiple variants supporting Thogoto virus polymerase activity, showing evolutionary plasticity across species.

DOI 10.1101/2024.09.16.613268

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ImmunologyFrontiers in ImmunologyPeer-reviewedJul 19, 2024

Multiple Unfolded Protein Response pathways cooperate to link cytosolic dsDNA release to Stimulator of Interferon Gene (STING) activation

Tiancheng Hu, Yiping Liu, Jeremy Fleck…·Judith A. Smith

This study identifies multiple UPR pathways that cooperate to link cytosolic dsDNA release to STING activation and IFN-β induction in response to ER stress.

2 citations

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