CCR2-driven monocyte recruitment is protective against radiotherapy-induced intestinal toxicity
Nabina Pun, Urszula Cytlak, Dave Chi Hoo Lee, Rita G. Domingues, Eleanor J. Cheadle, Duncan M. Forster, Clara H Whiteley, Jamie Honeychurch, Kaye Janine Williams, Gerard J. Graham, Matthew R. Hepworth, Mark A. Travis, Tim Illidge, Douglas P. Dyer
The paper shows that CCR2-driven monocyte recruitment reduces radiotherapy-induced intestinal toxicity by enhancing IL-17 production.
Mucosal Immunology · Oct 25, 2025Peer-reviewedImmunology