Matthew R. Hepworth

The paper introduces PIg-seq to study IgA-bound bacteria and finds widespread transcriptional responses, including changes in conjugation genes and prophages, linking IgA to horizontal gene transfer.

This study shows that cerebral ischaemic stroke alters mucosal IgA responses and host-commensal microbiota interactions, leading to changes in intestinal microbiota composition.

The paper shows that CCR2-driven monocyte recruitment reduces radiotherapy-induced intestinal toxicity by enhancing IL-17 production.

This study shows that meal timing affects gut circadian rhythms, with interval feeding disrupting IEC clock transcripts and microbiota rhythms.

This study shows that dermal gamma delta T cells migrate from the skin to the lungs during Nippostrongylus brasiliensis infection, balancing IL-17 and IFN-gamma responses to prevent lung damage.