Mark A. Travis

Inflammatory responses following CRISPR modification of the nuclear localisation sequence in endogenous interleukin-1α

This study disrupts the nuclear localisation sequence of endogenous IL-1α in mice and examines its effects on inflammatory responses, finding no significant changes in LPS-induced transcriptional signatures or IL-1 release.

CCR2-driven monocyte recruitment is protective against radiotherapy-induced intestinal toxicity

The paper shows that CCR2-driven monocyte recruitment reduces radiotherapy-induced intestinal toxicity by enhancing IL-17 production.

Star-polymers as potent broad-spectrum extracellular virucidal antivirals

This paper discovers a broad-spectrum, non-toxic polymer virucide effective against multiple viruses at nanomolar concentrations, showing efficacy in a murine RSV model.