Neutrophils induce effective antibody responses to the pneumococcal conjugate vaccine by inhibiting regulatory T cells
Essi Y. I. Tchalla, Anagha Betadpur, Andrew Y. Khalil, Elena Lopez, Manmeet Bhalla, Musea Chang, Elizabeth A. Wohlfert, Elsa N. Bou Ghanem
This study shows that neutrophils suppress regulatory T cells to enhance antibody responses to the pneumococcal conjugate vaccine in mice and humans.
Journal of Leukocyte Biology · Jul 31, 2026Peer-reviewedImmunology