Small things matter: Lack of extra-islet beta cells in Type 1 diabetes
Kathryn Murrall, Teifion Luckett, Christiana Lekka, Christine S. Flaxman, Rebecca C. Wyatt, Pouria Akhbari, Irina Kusmartseva, Stephanie L. Hunter, Pia Leete, Isabel Burn, Elena Osokina, James Shaw, Noel G. Morgan, Sarah J. Richardson
Image analysis of 262,832 pancreatic endocrine objects across 220 donors reveals that small beta-cell-only clusters are abundant in early childhood but virtually absent in type 1 diabetes.
bioRxiv · Apr 11, 2025 · PreprintPathology✦ In-depth digest