Noel G. Morgan

This study investigates JAKMIP1's role in neuronal IL-6/STAT3 signaling and its implications for Dup15q syndrome, finding that JAKMIP1 deficiency impairs signaling and neuritogenesis.

Image analysis of 262,832 pancreatic endocrine objects across 220 donors reveals that small beta-cell-only clusters are abundant in early childhood but virtually absent in type 1 diabetes.

This study shows that EVs deplete GGA2 in beta cells, causing Golgi acidification and altering the MHC class I immunopeptidome through premature cathepsin activation.

This study characterizes native human pancreatic mesenchymal stromal cells (npMSCs) in type 1 diabetes, finding increased npMSC density around insulin-containing islets and reduced density around insulin-deficient islets in diabetic individuals.

The paper quantifies DNA methylation changes in human fetal pancreas development, identifying developmental differentially methylated positions and their genomic distribution.

This paper evaluates 53 Tau antibodies for Western blot and immunohistochemistry, identifying those with high specificity and sensitivity for detecting Tau, including low-level and modified forms.

The paper identifies non-coding mutations in a regulatory element of HK1 that lead to inappropriate expression in pancreatic beta-cells and cause congenital hyperinsulinism.