Tumour-stroma signaling drives a reversible program with neural-like features in cancer-associated fibroblasts
Myriam Iliana Ibanez-Rios, Maëlle Batardière, Elham Dianati, Guillaume Serwe, Sajanth Kanagasingam, Alexandre Archambault-Marsan, Pierre Thibault, Marc Therrien, Vincent Quoc‐Huy Trinh, David J. H. F. Knapp
The paper identifies tumor-derived signals that induce a reversible neural-like program in cancer-associated fibroblasts and shows it is regulated by growth factors and MAPK/ERK signaling.
bioRxiv · Oct 9, 2026 · PreprintCancer Biology