Kinetic properties of optogenetic site-specific DNA recombination by LiCre-loxP
Alice Dufour, Hélène Duplus‐Bottin, Thomas Boukéké-Lesplulier, Eliane Casassa, Gérard Triqueneaux, Léo Tarbouriech, Camille Darthenay-Kiennemann, Agnès Dumont, Catherine Moali, Franck Vittoz, Daniel Jost, Gaël Yvert
This paper characterizes the kinetic properties of the optogenetic LiCre-loxP system using in vitro and in vivo experiments, revealing temperature-dependent efficiency and a model for recombination synapse formation.
Biology Open · May 14, 2026Peer-reviewedBioengineering