Catherine Moali

This study produces and characterizes recombinant procollagen I variants to elucidate the functional role of the α2(I) chain in fibril formation and proteolytic processing.

The paper determines the structure of PCPE-2 bound to BMP-1, revealing how PCPE-2 inhibits BMP-1 through a bipartite interaction involving its CUB domains.

This study shows that ascorbic acid and hypoxia regulate collagen biosynthesis through distinct mechanisms, with AA enhancing secretion via CXCL12-CXCR4 signaling and hypoxia increasing hydroxylation.

This paper characterizes the kinetic properties of the optogenetic LiCre-loxP system using in vitro and in vivo experiments, revealing temperature-dependent efficiency and a model for recombination synapse formation.