Gaël Yvert

This paper characterizes the kinetic properties of the optogenetic LiCre-loxP system using in vitro and in vivo experiments, revealing temperature-dependent efficiency and a model for recombination synapse formation.

The paper identifies trans-acting mutations in yeast that modulate gene expression noise in both intrinsic and extrinsic ways, revealing non-nuclear factors influencing nuclear gene expression.

The paper introduces a method to identify drug-sensitive protein-protein interactions in live cells using ERK1 as a case study, showing how inhibitory molecules affect these interactions.

The paper develops LiCre, a fast-responding light-inducible Cre recombinase, and demonstrates its efficiency in yeast and human cells.

The paper shows genetic variation in human B-cell surface protein expression dispersion, linking it to a specific SNP.

This study shows that the absence of SET-2 in C. elegans leads to progressive transcriptomic deregulation across generations, resulting in loss of germline identity and sterility.

This study measures the proliferation rates of yeast gene deletion mutants under periodic salinity stress, identifying genes that influence growth in fluctuating conditions.

The paper uses dynamic modeling of gene networks to interpret natural DNA variants by personalizing model parameters based on genotype, revealing how variants affect molecular regulation in yeast.