A bioprinted silk marrow niche reveals mechanical regulation of human megakaryopoiesis under genotoxic stress
Christian Andrea Di Buduo, Matteo Migliavacca, Michele Menotta, Elin Pernevik, Alessandro Malara, Santo Diprima, Giovanni Goggi, Claudia Del Fante, Monica Savio, Volodymyr Kuzmenko, Mauro Magnani, Alessandra Balduini
This study shows that a bioprinted silk marrow niche supports proper megakaryopoiesis and reduces DNA damage compared to 2D culture under genotoxic stress.
bioRxiv · Jun 19, 2026 · PreprintCell Biology