Author

Alessandro Malara

University of PaviaORCID 0000-0002-3396-3693Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Organism:human· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

Alessandra BalduiniiD· 3 shared Santo DiprimaiD· 2 shared Alessandro GulinoiD· 1 shared Annamaria AprileiD· 1 shared Carla MartinelliiD· 1 shared Caroline MartyiD· 1 shared Christian Andrea Di BuduoiD· 1 shared Claudia Del FanteiD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersCell Biology

Alessandra BalduiniORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Fibronectin silencing remodels the fibrotic bone marrow niche

Francesca Rossella Calledda, Vittorio Abbonante, Maria Francesca Testa, Delfina Tosi, Carla Martinelli, Santo Diprima, Roberta Gioia, Umberto Gianelli, Caroline Marty, Hana Raslová, Isabelle Plo, Dario Balestra, Mirko Pinotti, Alessandra Balduini, Alessandro Malara

This study shows that silencing fibronectin reduces fibrotic bone marrow niche remodeling and stromal activation in myelofibrosis models.

bioRxiv · Oct 19, 2026 · PreprintCancer Biology

A genetic anemia disentangles the dual effect of chronically reduced thrombopoietin on hematopoietic stem cells and bone marrow niche

Annamaria Aprile, Alessandro Malara, Mariangela Storto, Alessandro Gulino, Valeria Cancila, Gaia Morello, Silvia Sighinolfi, Laura Raggi, Stefano Beretta, Ivan Merelli, Sarah Marktel, Maurilio Ponzoni, Claudio Tripodo, Alessandra Balduini, Giuliana Ferrari

This study uses a genetic anemia model to show that reduced thrombopoietin affects hematopoietic stem cells and the bone marrow niche through direct and indirect mechanisms.

bioRxiv · Oct 9, 2026 · PreprintCell Biology

A bioprinted silk marrow niche reveals mechanical regulation of human megakaryopoiesis under genotoxic stress

Christian Andrea Di Buduo, Matteo Migliavacca, Michele Menotta, Elin Pernevik, Alessandro Malara, Santo Diprima, Giovanni Goggi, Claudia Del Fante, Monica Savio, Volodymyr Kuzmenko, Mauro Magnani, Alessandra Balduini

This study shows that a bioprinted silk marrow niche supports proper megakaryopoiesis and reduces DNA damage compared to 2D culture under genotoxic stress.

bioRxiv · Jun 19, 2026 · PreprintCell Biology