Author

Elina Starosvetsky

Technion – Israel Institute of Technology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Systems Biology· 2 Bioinformatics· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 4 Approach:statistical model· 4 Research Focus:differential expression· 3 Organism:human· 3 Research Focus:gene regulatory network inference· 2 Research Focus:cell type annotation· 1 Research Focus:deconvolution· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Shai S. Shen-OrriD· 4 shared Ayelet Alpert· 3 shared Adir Katz· 2 shared Renaud Gaujoux· 2 shared Shiran Gerassy-VainbergiD· 2 shared Tania Dubovik· 2 shared Yishai OfraniD· 2 shared Alexandra Blatt· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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4 shared papersSystems Biology

Shai S. Shen-OrrORCID

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4 papers

Recent·Most cited

A personalized network framework reveals predictive axis of anti-TNF response across diseases

Shiran Gerassy-Vainberg, Elina Starosvetsky, Renaud Gaujoux, Alexandra Blatt, Naama Maimon, Yuri Gorelik, Sigal Pressman, Ayelet Alpert, Haggai Bar‐Yoseph, Tania Dubovik, Benny Perets, Adir Katz, Neta Milman, Meital Segev, Yehuda Chowers, Shai S. Shen-Orr

The paper introduces a computational framework to identify predictive drug response axes across diseases using blood data, finding the RAC1-PAK1 axis predicts anti-TNF response in inflammatory bowel disease and rheumatoid arthritis.

Cell Reports Medicine · Dec 19, 2023Peer-reviewedSystems Biology

CytoPro: A computational platform for accurate and robust assessment of cell contributions in bulk expression from diverse tissues and conditions

Adir Katz, Renaud Gaujoux, Hadas Orly, Elina Starosvetsky, Roye Rozov, Yoni Rabinovitch, Benny Halberstadt, Liron Bar, Yael Spector, Naama Wald, Chanan Rubin, Yair Benita, Shiran Gerassy-Vainberg, Shai S. Shen-Orr

CytoPro is a deconvolution platform that accurately estimates cell-type composition from bulk gene expression, outperforming existing tools in accuracy and robustness.

bioRxiv · Aug 19, 2021 · PreprintBioinformatics

High Resolution Comparison of Cancer-Related Developmental Processes Using Trajectory Alignment

Ayelet Alpert, Elina Starosvetsky, Michal Hayun, Yishai Ofran, Shai S. Shen-Orr

devMap enables comparison of cancer-related developmental processes across patients by aligning high-dimensional trajectories to a common backbone, revealing conserved signaling patterns in AML.

bioRxiv · Nov 14, 2018 · PreprintSystems Biology

Architecture of a multi-cellular polygenic network governing immune homeostasis

Tania Dubovik, Elina Starosvetsky, Benjamin LeRoy, Rachelly Normand, Yasmin Admon, Ayelet Alpert, Yishai Ofran, Max G’Sell, Shai S. Shen-Orr

The paper identifies a polygenic network governing immune homeostasis using mass-cytometry data from 55 mouse strains, showing 52% of trait genes predict phenotype and revealing multi-cellular regulatory complexity.

bioRxiv · Sep 23, 2018 · PreprintGenetics