Author

Tania Dubovik

Technion – Israel Institute of Technology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Ayelet Alpert· 2 shared Elina Starosvetsky· 2 shared Shai S. Shen-OrriD· 2 shared Adir Katz· 1 shared Alexandra Blatt· 1 shared Benjamin LeRoy· 1 shared Benny Perets· 1 shared Haggai Bar‐YosephiD· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersSystems Biology

Ayelet Alpert

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2 papers

Recent·Most cited

A personalized network framework reveals predictive axis of anti-TNF response across diseases

Shiran Gerassy-Vainberg, Elina Starosvetsky, Renaud Gaujoux, Alexandra Blatt, Naama Maimon, Yuri Gorelik, Sigal Pressman, Ayelet Alpert, Haggai Bar‐Yoseph, Tania Dubovik, Benny Perets, Adir Katz, Neta Milman, Meital Segev, Yehuda Chowers, Shai S. Shen-Orr

The paper introduces a computational framework to identify predictive drug response axes across diseases using blood data, finding the RAC1-PAK1 axis predicts anti-TNF response in inflammatory bowel disease and rheumatoid arthritis.

Cell Reports Medicine · Dec 19, 2023Peer-reviewedSystems Biology

Architecture of a multi-cellular polygenic network governing immune homeostasis

Tania Dubovik, Elina Starosvetsky, Benjamin LeRoy, Rachelly Normand, Yasmin Admon, Ayelet Alpert, Yishai Ofran, Max G’Sell, Shai S. Shen-Orr

The paper identifies a polygenic network governing immune homeostasis using mass-cytometry data from 55 mouse strains, showing 52% of trait genes predict phenotype and revealing multi-cellular regulatory complexity.

bioRxiv · Sep 23, 2018 · PreprintGenetics