NeurosciencebioRxivPreprint
Deciphering the Role of Aggrecan in Parvalbumin Interneurons: Unexpected Outcomes from a Conditional ACAN Knockout That Eliminates WFA+ Perineuronal Nets
Sverre Grødem, Elise Holter Thompson, Malin Benum Røe…·Kristian Kinden Lensjø
This paper investigates the role of Aggrecan in PV+ interneurons by creating a conditional knockout model and finds that its absence does not affect electrophysiological properties but alters behavioral strategies and anxiety levels.
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