Author
Memorial Sloan Kettering Cancer Center
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
5 papers
Recent·Most cited
Jake June-Koo Lee, Sohrab Salehi, Matthew A. Myers…·Sohrab P. Shah
The paper analyzes the evolutionary trajectories of high-level copy-number amplifications in cancer cell genomes to distinguish between extrachromosomal and intrachromosomal amplification mechanisms.
Marc J. Williams, Ignacio Vázquez-Garćıa, Grittney K. Tam…·Sohrab P. Shah
This study tracks clonal evolution of drug resistance in ovarian cancer using structural variants in cfDNA, finding polyclonal resistance with dominant high-fitness clones and genomic features linked to drug resistance.
Katarzyna Kulej, Asher Preska Steinberg, Jinxin Zhang…·Alex Kentsis
The paper introduces ProteomeGenerator3, an end-to-end proteogenomics method that detects non-canonical proteoforms in cancer using long-read transcriptomics and multi-dimensional proteomics.
Andrew McPherson, Ignacio Vázquez-Garćıa, Matthew A. Myers…·Sohrab P. Shah
This study shows that ongoing whole-genome doubling in ovarian cancer promotes cell diversity and immune dysregulation through chromosomal instability and quiescent states.
Sohrab Salehi, Emily E. Stroobant, Hannah Lees…·Santosha Adipudi Vardhana
The paper identifies impaired T cell priming and KLF2-dependent quiescence in gastric cancer draining lymph nodes as mechanisms limiting immune responses.