Developmental BiologyStem Cell ReportsPeer-reviewed
WNT signaling in human pluripotent stem cells promotes HDAC2-dependent epigenetic programs and development of retinoic acid-responsive mesoderm
Bao Thai, Elizabeth J. Sargent, Stephanie A. Luff…·Deepta Bhattacharya
This study shows that WNT signaling in hPSCs promotes mesoderm development through HDAC2-dependent epigenetic programs and RA responsiveness, enhancing T cell generation.