Cancer BiologybioRxivPreprint
The enzyme glutamate-cysteine ligase (GCL) is a target for ferroptosis induction in cancer
John K. Eaton, Priya Chatterji, Laura Furst…·Vasanthi S. Viswanathan
This study identifies GCL inhibition as a strategy to induce ferroptosis in cancer cells, introducing novel inhibitors with potent cellular activity.
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