Coordinated Tbx3/Tbx5 transcriptional control of the adult ventricular conduction system
Ozanna Burnicka-Turek, Katy Anne Trampel, Brigitte Laforest, Michael Broman, Xinan Holly Yang, Zoheb Khan, Eric Rytkin, Binjie Li, Ella Schaffer, Margaret Gadek, Kaitlyn M Shen, Igor R. Efimov, Ivan P. G. Moskowitz
This study shows that Tbx3 and Tbx5 work together to control the function and molecular identity of the adult ventricular conduction system in mice, leading to conduction defects when both are missing.
eLife · Jul 24, 2025Peer-reviewedDevelopmental Biology