mRNA interactions with disordered regions control protein activity
Yang Luo, Supriya Pratihar, Ellen Horste, Sibylle Mitschka, Antonia S. J. S. Mey, Hashim M. Al‐Hashimi, Christine Mayr
The paper shows that mRNAs interact with disordered regions of proteins like MYC to control their activity by enabling specific protein complexes formed in translation sites called TIS granules.
bioRxiv · Feb 18, 2023 · PreprintMolecular Biology