Supriya Pratihar

The paper shows that the disordered C-terminal segment of Skp1, H8, nucleates helices but limits their propagation through a charge-sensitive rheostat, maintaining conformational flexibility.

The paper characterizes the multi-timescale structural dynamics of the p53 transactivation domain using NMR and simulations, revealing a hierarchical energy landscape.

The paper shows that an A-T Hoogsteen base pair forms in naked DNA hairpins without protein binding, and identifies a DNA-specific motif stabilized by this pairing.

The paper shows that mRNAs interact with disordered regions of proteins like MYC to control their activity by enabling specific protein complexes formed in translation sites called TIS granules.